Prenatal exposure and risk of medication in autism spectrum disorder.

Authors

  • Muhammad Ahmed The University of Lahore.
  • Hamza Manzoor Hope Executive Hospital, Amin Town.
  • Saira Zaman Lahore Medical and Dental College/ Ghurki Trust Teaching Hospital, Lahore.
  • Athar Adnan Uppal Lahore Medical and Dental College/ Ghurki Trust Teaching Hospital, Lahore.
  • Nasir Riaz King Edward Medical University Lahore.
  • Aysha Nauman Rashid Latif Khan University and Medical College.

DOI:

https://doi.org/10.29309/TPMJ/2026.33.01.9923

Keywords:

Autism Spectrum Disorder, Communicative Disorder, Prenatal Exposure

Abstract

Objective: The research aims to investigate correlations between prenatal medication exposure and ASD risk. Study Design: Cross-Sectional Observational Study. Setting: Department of Speech Language Pathology, The University of Lahore. Period: 22nd April 2024 22nd October 2024. Methods: Involving 45 mothers of autistic children. The research spanned 12 months, employing a purposive sampling technique and a self-designed questionnaire. Data analysis utilized SPSS software, focusing on demographic characteristics and questionnaire responses. Results: Findings reveal a variety of factors potentially associated with ASD, including abrupt medication changes (26.7%), pre-clampsia (35.6%), maternal age (60% within 25-30 age group), neurological conditions (37.8%), cousin marriages (37.8%), and complications during delivery (22.2%). The study emphasizes the complexity of ASD and highlights potential risk factors. Conclusion: The research concludes that while no specific prenatal factor is implicated in ASD etiology, certain associations suggest that exposure to pregnancy complications may increase the risk. The study underscores the need for a nuanced understanding of ASD and early intervention strategies.

Author Biographies

Muhammad Ahmed, The University of Lahore.

MSSLP, Assistant Professor Rehabilitation Sciences, 

Hamza Manzoor, Hope Executive Hospital, Amin Town.

MS (Psychology), Consultant Speech Language Pathologist, 

Saira Zaman, Lahore Medical and Dental College/ Ghurki Trust Teaching Hospital, Lahore.

MBBS, FCPS, Associate Professor, 

Athar Adnan Uppal, Lahore Medical and Dental College/ Ghurki Trust Teaching Hospital, Lahore.

MBBS, FCPS, Professor ENT, 

Nasir Riaz, King Edward Medical University Lahore.

FCPS, Assistant Professor ENT, 

Aysha Nauman, Rashid Latif Khan University and Medical College.

FCPS, Assistant Professor ENT, 

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Published

2026-01-03

Issue

Section

Origianl Article