Protective effects of natural products in neurodegeneration: A narrative review.

Abstract

This systematic review aims to analyze published studies from databases such as PUBMED, Google Scholar and Research Gate, while focusing on the role of bioactive components found in the natural medicinal products in Grape, Honey, Pomegranate juice and Moringa Oleifera in neuroprotection. The literature search was done from 2019 till 2025 with key words of natural products, neuroprotections and neurodegeneration and more than 50 full articles were included. This review highlights the therapeutic potential of natural products and their bioactive compounds in providing neuroprotective effects against the pathologies associated with neurodegenerative diseases. Neurodegenerative diseases of the nervous system manifested through various syndromes, with progressive dementia being the predominant symptom in mostly cases. The bioactive compounds include vitamins, minerals, carotenoids, polyunsaturated fatty acids, and polyphenols, alkaloids, and some other compounds found, will be the primary focus of this document. This document provides the evidence basis to determine the nutritional benefits of these medicinal products in improving the health and well-being of various groups.