VITAMIN D ASSOCIATION

MAJOR RISK FACTORS OF CARDIOVASCULAR DISEASE

Abstract

OBJECTIVE: The target of this study to focus, vitamin D level is the significant risk
factors for the patients with cardio vascular disease at Liaquat University Hospial Hyderabad /
Jamshoro. Materialand Methods: This observational study was done at cardiology department
of Liaquat University Hospital Hyderabad. All the cases with history of congenital heart disease,
pregnancy, malignancy, renal failure and chronic liver disease, were excluded from the study.
Complete medical history was taken, and major risk factors of the cardiovascular disease
including, diabetes, smoking, family history, hypertension, hypercholestremia, dyslipidemia
and history of alcohol consumption and others were documented. Serum VD level was tested
by blood samples from research laboratory of Liaquat Medical hospital Hyderabad, and all the
results were noted on the Performa according to the risk factors. Consequences of VD level
were arranged by criteria, that’s taken from the study of Satish Karur etal.10 Results: Total 100
patients were incorporated in the study with the mean age of 48.2+ 12.4. Male were found in
the majority. According to distribution of heart disease of his study ischemic heart disease had
noted commonest58%. In the hypertensive patients VD deficiency had noted in 39. 63%. In
smoker patients VD deficiency was noted in 52.77%. In patients with hypercholestremia 50.0%,
Alcoholic patients were found with deficiency of VD were 50.0%. In patients with obesity 57.14%.
In the diabetic patients deficiency 15.0%, insufficiency 50.0% and sufficiency was seen 35.0%.
In the Patients of dyslipidemia deficiency5.0%, insufficiency 50.0% and sufficiency was seen
45.0%. Patients with family history of cardiovascular disease having deficiency 25.0% of the
cases, insufficiency 12.50% while sufficiency in 62.50% in the cases. Conclusion: In this study
we concluded that VD deficiency in one of the major risk factor for cardiovascular disease;
its possible association was found in this study with many risk factors of heart diseases. Like
our study there is very need of experimental and prospective more studies, to find out the
mechanism undergoing increasing cardiovascular risk, and prevent the cardiovascular disease.