Comparison of outcome in patients undergoing elective cesarean delivery with intravenous acetaminophen versus placebo.
DOI:
https://doi.org/10.29309/TPMJ/2025.32.06.8808Keywords:
Analgesia Requirement, Caesarean Delivery Pain, IV Acetaminophen, Pain ControlAbstract
Objective: To see effect of IV acetaminophen in post caesarean delivery to control pain in cases with general anesthesia. Study Design: Randomized Controlled Trail. Setting: Department of Obstetrics and Gynecology, University Teaching Hospital, Gujranwala. Period: Aug 31, 2019 till April 30, 2020. Methods: All cases meeting inclusion criteria was enrolled and underwent elective cesarean section. Then they were randomly divided to receive either 15 mg/kg intravenous acetaminophen (n = 146) or normal saline (n = 146) fifteen minutes before endotracheal intubation. Pain was measured after 6 hours of C-section. SPSS version 22 was used to analyze the data. Results: The mean age of cases in group-A was 26.59 ± 4.95 years and in group-B was 26.44 ± 4.72 years. The mean gestational age in group-A and group-B was 39.54 ± 1.19 weeks and 39.38 ± 1.08 weeks. The mean pain in group-A was 4.98 ± 1.01 and in group-B was the mean pain was 6.18 ±1.30. The mean pain in group-A (acetaminophen group) was statistically lower than group-B (placebo), p-value < 0.001. Conclusion: It is concluded that IV acetaminophen is effective in controlling the pain in cases with general anesthesia after caesarean delivery. Hence in future this non-opioid analgesic without potential adverse effects can be used. This will surely reduce the analgesia requirement and hospital stay.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 The Professional Medical Journal

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.