Evaluation of platelet parameters in HBsAg positive somalian patients.

Abstract

Objective: To evaluate platelet parameters in HBsAg-positive Somalian patients. Study Design: Cross-sectional study. Setting: Recep Tayyip Erdogan Hospital in Mogadishu, Somalia. Period: January 2017 to November 2019. Methods: Three hundred sixty five HBsAg-positive patients and 544 HBsAg-negative healthy individuals included in this study. HBsAg-positive patients were divided into two groups according to their HBV-DNA levels. Complete blood count results of patients and healthy controllers were obtained retrospectively from the information processing system in the hospital. Results: The average platelet count in HBsAg-positive patients and healthy controls was 246.8±76.0x103/mm3 and 283.1±67.7 x103/mm3, respectively and the difference was statistically significant (p<0.001). There was a statistically significant difference in mean platelet volume values between the two groups (p<0.001). There was statistically significant difference between platelet distribution width values of HBsAg-positive patients and HBsAg-negative group (p < 0.001). Conclusion: In this study, we found significant decrease in platelet count and mean platelet volume level. We also found significant increase in platelet distribution width level in HBsAg-positive Somalian patients.