TIMI RISK SCORES

FREQUENCY OF DOUBLE VESSEL CORONARY ARTERY DISEASE IN DIFFERENT TIMI SCORES IN PATIENTS PRESENTING WITH NON ST-ELEVATION ACUTE CORONARY SYNDROME AT GULAB DEVI CHEST HOSPITAL

Abstract

Background: Thrombolysis In Myocardial Infarction (TIMI) risk score predicts
adverse clinical outcomes in patients with non–ST-elevation acute coronary syndromes
(NSTEACS). Whether this score correlates with the coronary anatomy is unknown. Objective:
To determine the frequency of low, moderate and high TIMI risk score in patients of NSTEACS
and to compare the frequency of two vessel coronary artery disease on angiography with
low, moderate and high TIMI risk scores in patients of NSTE-ACS. Study design: This was a
cross sectional study. Setting: Department of Cardiology, Gulab Devi Chest Hospital, Lahore.
Duration: Six months. Patients and Methods: Total 170 patients were included in the study.
Patients’ selection was done with the help of a pre-defined inclusion and exclusion criteria. TIMI
risk score was calculated for each patient and patients were categorized into low, moderate and
high risk groups (as per operational definition). Patients were further evaluated with coronary
angiograms to assess the double vessel CAD. All angiographies were performed by a single
physician. Data analysis was done on SPSS version 17. Results: Mean age of our patients was
54.81±10.55 years. Gender distribution shows that there were 106(62%) male and 64(38%)
female patients. TIMI score risk classification showed that among 50(29.4%) patients TIMI risk
score was low, among 107(62.9%) patients it was moderate and in 13(7.6%) patients it was
high. There were 105(62%) patients who had two vessel coronary artery disease. Among 105
patients who had two vessel coronary artery disease, 25(23.8%) had low TIMI score, 69(65.7%)
had moderate and 11(10.5%) of the patients had high TIMI score. Conclusion: In patients
with non-ST-elevation acute coronary syndrome undergoing cardiac catheterization, the TIMI
risk score is significantly associated with two vessel coronary artery disease. So it should be
recommended that a routine invasive strategy be carried in patients with moderate or higher
TIMI risk score.