To determine the frequency of prostate cancer in patients of suspicion of prostate cancer.

Abstract

Objective: To determine the frequency of prostate cancer among patients with clinical suspicion and analyze the impact of age and symptom duration on diagnostic outcomes. Study Design: Cross-sectional study. Setting: Bilawal Medical College for Boys, Liaquat University of Medical and Health Sciences (LUMHS), Jamshoro. Period: October 1, 2023, to March 31, 2024. Methods: The study included 101 male patients aged 50 years and older who presented with elevated prostate-specific antigen (PSA) levels, abnormal digital rectal examination (DRE) findings, or relevant symptoms. Data were collected retrospectively from medical records, including demographic details, PSA levels, symptom duration, DRE findings, prostate volume, and biopsy results. Prostate cancer diagnosis was confirmed through histopathological examination. Stratified analyses by age groups (50-60 years and >60 years) and symptom duration (1-3 months and >3 months) were conducted using chi-square tests. Results: Prostate cancer was diagnosed in 16.8% of patients. Age and symptom duration were not significantly associated with prostate cancer frequency (p=0.828 and p=0.264, respectively). The mean age was 63.8 years, and the mean prostate volume was 54.7 ml. Conclusion: Age and symptom duration do not significantly influence prostate cancer risk among suspected patients. Comprehensive diagnostic strategies incorporating multiple risk factors are recommended to improve detection and management.