CHRONIC VIRAL HEPATITIS C INFECTION;

Frequency of impaired glucose tolerance in patients

Abstract

Objective: The objective of the study was to measure the frequency of impaired glucose tolerance (IGT) in patients having
chronic hepatitis C at medical outpatient department (OPD) of Allied hospital Faisalabad. Sample technique: Non probability consecutive
sampling. Duration of study: Duration of study was 6 months with first patient enrolled on 3.02.2010 and last patient enrolled on 07-08-
2010. Setting: Medical (OPD) Outpatient Department of Allied Hospital, Faisalabad. Subjects: 375 patients with chronic hepatitis C,
coming in Medical OPD of Allied hospital Faisalabad were enrolled. Methods: 375 patients diagnosed as having chronic hepatitis C
coming in Medical OPD of Allied hospital Faisalabad, were included in the study. Fasting and two hours after glucose load blood sample
were collected in sterilized syringes and was tested for fasting blood glucose (FBS) and random blood glucose level (RBS). Results: In
this study 375 patients having HCV positive on Elisa were enrolled. Out of 375 patients with chronic hepatitis C, 143 (38.1%) were found
to have IGT while 232 (61.9%) were having no IGT. There was significant association between chronic hepatitis C and development of IGT.
Conclusions: It is concluded that there is close association in the development of IGT in patients with chronic hepatitis C.