Comparison of effectiveness of combination of xylocaine and dexmedetomidine with xylocaine alone in biers block of upper limb.


  • Tahir Nazeer Azrah Naheed Medical College,
  • Asif Rashid Alamgir AFM&DC.
  • Sahir Shafiq FMU.
  • Umair Ahmed Aziz Fatimah Hospital and Medical College Faisalabad.
  • Riaz Hussain Rahber Medical and Dental College, Lahore.
  • Umer Farooq Gujranwala Medical College, Gujranwala.



Anesthesia, Bier's Block, Dexmedetomidine, Effectiveness, Upper Limb, Xylocaine


Objective: To evaluate two groups (combination versus xylocaine alone) in terms of onset of motor block, duration of block, and postoperative analgesia following the release of the tourniquet. Study Design: Quasi Experimental study. Setting: Chaudhary Muhammad Akram Teaching & Research Hospital. Period: 01 June 2023 to 30 Nov 2023. Material & Methods: Quasi experimental study design with a sample of total 80 patients divided into two groups of 40 each (xylocaine alone & combination of xylocaine and dexmedetomidine) were selected by using non probability convenient sampling technique. Results: Combining dexmedetomidine with xylocaine in Bier's block for upper limb surgery demonstrated significant advantages. Group B exhibited faster onset (3.8 min), prolong motor block, and prolonged postoperative analgesia (12.4 hrs) compared to group A (xylocaine alone: 5.2 min onset & shorter postoperative analgesia 6.8 hrs). Dexmedetomidine enhanced post-operative pain control, showcasing its effectiveness in improving outcomes for Bier's block procedures. Conclusion: Dexmedetomidine enhances Bier's block with xylocaine, providing faster onset, extended motor block, and superior post-operative analgesia for upper limb surgery.

Author Biographies

Tahir Nazeer, Azrah Naheed Medical College,

MBBS, DA, MCPS, FCPS, MS Anae (UHS), Professor Anaesthesia, 

Asif Rashid Alamgir, AFM&DC.

MBBS (PU), DA (PU), MCPS (Anaes), MS (Anaes) UHS, Associate Professor, 

Sahir Shafiq, FMU.

MBBS (UHS), FCPS, Assistant Professor Anaesthesia, 

Umair Ahmed, Aziz Fatimah Hospital and Medical College Faisalabad.

MBBS (UHS), FCPS, (Anesthesia), Senior Registrar Anesthesia, 

Riaz Hussain, Rahber Medical and Dental College, Lahore.

MBBS, DA, FCPS, MSC, Ex HOD/Professor Anaesthesia, 

Umer Farooq, Gujranwala Medical College, Gujranwala.

MBBS, FCPS, MSC, Assistant Professor Anaesthesia,