Frequency of Ventilator associated Pneumonia (VAP), Central line associated Blood Stream Infections (CLABSI) and Catheter Related UTI in PICU - A single center experience from Lahore.

Abstract

Objective: To assess the incidence of catheter-related urinary tract infections (UTIs), central line-associated blood stream infections (CLABSIs), and ventilator-associated pneumonia (VAP) in the paediatric intensive care unit (PICU). Study Design: Retrospective Cross sectional Study. Study Design: Pediatric Intensive Care Unit, Fatima Memorial Hospital, Lahore. Period: January 10, 2023 to July 9, 2023. Methods: All 120 children of either gender admitted at PICU having age 1 month to 12 years who stayed in PICU for ≥48 hours were included in study. Data was recorded on the proforma containing basic demographic information along with diagnosis, mechanical ventilation, central line, urinary catheter and associated infections with information related to length of stay and outcome of the children. SPSS v25 was used to input and analyse the data. All of the variables were subjected to a descriptive analysis. Using stratification, we were able to regulate for potential moderators of the effects, such as age and gender. Chi-square/Independent t-tests were performed after stratification, with a p-value 0.05 indicating statistical significance. Results: Total 120 children admitted at PICU having age 1 month to 12 years who stayed in PICU for ≥48 hours were included in study. Gender distribution showed that, 77(64.2%) were males and 43(35.8%) were females. The mean age of the children was 26.6±31.95 months. The mean stay in PICU was 4.82±4.19 days and mean stay in hospital was 5.98±4.08 days. Among 120 children, 21(17.5%) were on ventilator and among them, 11(52.4%) had ventilator associated pneumonia, 14(11.7%) had CVL and 10(8.3%) had BSI and among them, 5(50.0%) had CVL associated BSI, while 22(18.3%) had catheter insertion and among them, 6(27.3%) had CA-UTI. According to outcome of children, 9(7.5%) expired. Conclusion: For developing countries, active surveillance is essential to reduce the burden of Healthcare-associated infections (HAIs) in high risk groups.