The postprandial glucose-lowering effect of dietary fiber (Psyllium Husk) in patients with type 2 diabetes mellitus.

Abstract

Objectives: To compare the mean reduction in postprandial plasma glucose in patients with diabetes mellitus type 2 by dietary fibre (psyllium husk) to those not using dietary fibre (psyllium husk) and on standard treatment. Study Design: Randomized Controlled Trial. Setting: Department of Medicine, Allied Hospital, Faisalabad. Period: 30^th November 2022 to 29^th May 2023. Material & Methods: A total of 60 type 2 diabetes mellitus patients of both genders, age >18 to 60 years, diagnosed with DM for more than two years, were selected. Patients undergoing insulin therapy, history of DSF allergy, gastrointestinal surgery, and pregnant or lactating women were excluded. Group A received soluble ffibre10.5 g daily for 12 weeks of intervention and standard medications oforDM. Postprandial glucose was checked after 2 hours of meal. In comparison, Group B did not receive any food supplements throughout the intervention period and continued regular diets. The outcome of Blood samples was obtained in terms of mean reduction in postprandial glucose. Results: Mean reduction in Postprandial glucose in Patients with type 2 diabetes mellitus by dietary fibre (psyllium husk) was 14.33 ± 2.04 mmol/l, and in those who are not using dietary fibre (psyllium husk) and on standard treatment, it was 10.83 ± 1.95 mmol/l (p-value = 0.0001). Conclusion: This study concluded that the mean reduction in Postprandial glucose in Patients with type 2 diabetes mellitus by dietary fibre (psyllium husk) is relatively high.