Exploring the relationship between family history of type 2 diabetes mellitus and anthropometric, blood sugar, and lipid parameters in normal individuals: A comparative study.

Abstract

Objective: To examine the anthropometric, blood sugar, and lipid profiles of healthy adults, including those with and those without a history of type 2 diabetes mellitus. Study Design: Case-control study. Setting: Peoples University of Medical & Health Sciences for Women (PUMHS) in Nawabshah. Period: October 1^st 2022 to 31^st March 2023. Material & Methods: The research included 110 participants. 55 of them had at least one parent with type 2 diabetes mellitus, and the other 55 did not. Males and females between the ages of 18 and 25 were present in the study. The following measurements were compared: fasting blood sugar, lipid profile, waist height to hip ratio, and body mass index. Results: This case-control study compares offspring with and without a family history of type 2 DM to determine if there are any anthropometric or metabolic differences. Participant with a family history of type 2 DM showed higher BMI, WC, and WHtR according to the anthropometric measurements. Statistically significant differences were found in their BMI (P-value <0.0001). Even though BMI showed a significant difference, the mean value did not fit into the criteria to be categorized as obese. Conclusion: The present research has shown that people with a family history of type 2 diabetes mellitus are overweight and have abnormal lipid profiles even before they manifest overt type 2 DM.