Correlation of monocytopenia with aging in COVID-19 infected patients.


  • Sana Rasheed Chaudhry Ameer-ud-din Medical College, Lahore. 
  • Zunnera Rashid Akhtar Saeed Medical College, Rawalpindi.
  • Erum Rashid Watim Medical College, Rawat.
  • Sabeen Shakir Akhtar Saeed Medical College, Rawalpindi.
  • Aenza Asif Mrgalla Institute of Health Sciences. Islamabad.
  • Faiza Rasheed Albadr Hospital Dubai.



Aging, Cytokines, COVID-19, Monocyte Count, Reduction


Objectives: To observe the effect of aging on monocyte count in COVID-19 infected patients. Study Design: Observational study. Setting: Rawal Institute of Health Sciences Islamabad, Pakistan Institute of Medical Sciences Islamabad. Period: April 2021 till July 2021. Material & Methods: Adult humans of total 100 in numbers, suffering from corona virus with positive PCR test were selected. They were divided in two groups with 50 patients in group A and 50 patients in group B. Inclusion criteria was COVID-19 infected patients belonging to both genders without any blood disorder. All adults below the age of 18 years with blood disorder diseases were excluded. The age limit in group A was below 50 years and in group B was above 50 years. Monocyte count of all the patients was noted from the record in the laboratory of Rawal institute of health sciences and Pakistan institute of Medical sciences Islamabad. The age of the patients was confirmed from their CNIC. Results: Data was checked for normality by using Shapirowilk test of normality and comparison of monocyte count in between two groups was done by using Mann Whitney U test a significant difference was seen. Monocyte count in group A was 172/ µl and in group B was 122/ µl of blood. The mean age in group A was 32.3 years and in group B was 65.9 years. The p value of 0.00 shows a significant correlation of aging with monocytopenia. Conclusion: Corona virus infected patients with increased age (> 50) years showed more reduction in monocyte count as compared to patients with lower age (< 50) years.

Author Biographies

Sana Rasheed Chaudhry, Ameer-ud-din Medical College, Lahore. 

MBBS. M.Phil (Physiology), Assistant Professor Physiology, 

Zunnera Rashid, Akhtar Saeed Medical College, Rawalpindi.

MBBS. M.Phil (Pharmacology), Associate Professor Pharmacology, 

Erum Rashid, Watim Medical College, Rawat.

MBBS. M.Phil (Biochemistry), Associate Professor Biochemistry, 

Sabeen Shakir, Akhtar Saeed Medical College, Rawalpindi.

MBBS. M.Phil (Pharmacology), Professor Pharmacology, 

Aenza Asif, Mrgalla Institute of Health Sciences. Islamabad.

Doctor of Physiotherapy 3rd Year Student of (DPT), Physiotherapy, 

Faiza Rasheed, Albadr Hospital Dubai.

MBBS. FCPS, Consultant Ophthalmologist,