Seroprevalence of transfusion- transmissible infections by type and their distribution across gender in blood donors, a regional blood center study, Pakistan.


  • Samina Qadir Gomal Medical College.
  • Anil Iqbal Alizai Gomal Medical College.
  • Hafsa Shah Gomal Medical College.
  • Ayesha Naeem Hayatabad Medical Complex, Peshawar.
  • Hira Naeem PIMS Hospital.
  • Kamran Waheed Hayatabad Medical Complex, Peshawar.



Blood Transfusion, Blood Donors, Hepatitis B, Malaria, Prevalence


Objective: To determine the prevalence and distribution by gender of Transfusion transmissible infections (TTIs) in blood donors. Study Design: Cross-sectional study Setting: Department of Community Medicine, G.M.C. Period: July 18, 2022 to November 18, 2022. Material & Methods: The data collecting tool was a structured proforma. A sample of 3329 was calculated with a 0.71% margin of   error, a 95% confidence level, and an expected prevalence of TTIs of 4.61%. Consecutive non probability sampling technique used. Nominal variables were gender, type of donors, presence of TTIs and types of TTIs. Counts and percentages with 95% confidence intervals were used to describe the prevalence and distribution. Chi-square goodness of fit was used to compare expected values with observed values. SPSS version 21 was used for data analysis. Results: Out of sample of 3329, TTIs positive cases were 174 (5.22%) with 95% CI of 4.51- 5.93%. All the positive cases were males. The prevalence for Hepatitis B, Hepatitis C, HIV, Syphilis, and Malaria was 2.2%, 0.9%, 0.3%, 1.9%, and 0.1% respectively. Our observed values for Hepatitis B&C, HIV and malaria were not statistically significantly different from expected values except for syphilis. Conclusion: Prevalence of TTIs was 5.22% with significantly higher prevalence of syphilis as compared to expected prevalence.

Author Biographies

Samina Qadir, Gomal Medical College.

MBBS, MCPS, Associate Professor Community Medicine, 

Anil Iqbal Alizai, Gomal Medical College.

MBBS, MPH, Demonstrator Community Medicine, 

Hafsa Shah, Gomal Medical College.

Final Year MBBS Student, 

Ayesha Naeem, Hayatabad Medical Complex, Peshawar.

MBBS, TMO Medicine, 

Hira Naeem, PIMS Hospital.

MBBS, Medical Officer, 

Kamran Waheed, Hayatabad Medical Complex, Peshawar.

MBBS, FCPS, TMO Ophthalmologist,