Influence of thyroid hormones and effect of treatment choice on the quality of life of hyperthyroid patients.


  • Javeria Salman Majee Hospital Hyderabad.
  • Ayesha Iqbal Indus Hospital.
  • Shakeel Ahmed Dow University of Healht Sciences, Karachi.
  • Sadia Naveed Abbasi Gul Medical Center Nawab Shah.
  • Heena Jilani Ziauddin University, Karachi.
  • Muhammad Siddiq Siddiqui Dow University of Healht Sciences, Karachi.



Euthyroidism, Hyperthyroidism, Quality of Life


Objective: To evaluate the influence of thyroid hormones as well as the effect of treatment choice on the quality of life of patients visiting / admitted in tertiary healthcare centers in Karachi, Sindh Pakistan. Study Design: Cross-sectional study. Setting: Rafae Aam General Hospital Federal Area Karachi, Sindh, Pakistan. Period: March 2022 to June 2022. Material & Methods: Patient’s data related to their socio-demographic and clinical details was collected by using a pre-tested written questionnaire. Brazilian version of 36-Item Short Form Health Survey questionnaire was completed by all the study participants. Results: Total 337 participants were included in the study. Mean age of the study participants was 34.03 ± 10.06. Majority of them were females while most of them belonged to the age group of 18-29 years. Most of our study participants were urban residents, married, having no any formal education and suffering from comorbidities. Based on clinical examination, 272 (80.7%) patients were found euthyroidism while 65 (19.3%) were hyperthyroid. Thus, hyperthyroid patients displayed a greater toll on the quality of life, particularly in areas of physical (59.62 vs. 82.81; p<0.05) as well as emotional (61.54 vs. 82.81; p<0.05) functioning. Conclusion: This study concludes that hyperthyroid patients have a significant quality of life impairment, particularly in the physical and emotional domains. Moreover, regardless of the findings of the serum thyroid hormone levels, quality of life of hyperthyroid patients is compromised.

Author Biographies

Javeria Salman, Majee Hospital Hyderabad.

MCPS, Diploma in Diabetes and Endocrinology, Diabetologist, 

Ayesha Iqbal, Indus Hospital.

MBBS, MCPS, Diploma Diabetes and Endocrinology Family Medicine, Senior Specialist Family Medicine, 

Shakeel Ahmed, Dow University of Healht Sciences, Karachi.

MBBS, MD (Diabetes), MACP (USA), Consultant Diabetologist and Endocrinologist, 

Sadia Naveed Abbasi, Gul Medical Center Nawab Shah.

MBBS, FCPS (Family Medicine), Diploma in Diabaties and Endocrinology, Diabetologist, 

Heena Jilani, Ziauddin University, Karachi.

MBBS, M.Phil (Pathology), Postgraduate Trainee Pathology, 

Muhammad Siddiq Siddiqui, Dow University of Healht Sciences, Karachi.

MBBS, Post Graduate Diploma Training in Critical Care Medicine, Diabetologist,