The pattern of hematological parameters in type 2 diabetes.

Abstract

Objective: To study the pattern of hematological parameters in Type 2 diabetic patients. Study Design: Observational Cross Sectional. Setting: Creek General Hospital, Karachi. Period: June to December 2021. Material & Methods: Two hundred and five diabetic patients were selected by convenient sampling technique. Inclusion Criteria was individuals more than 30 years old, diagnosed with Type 2 DM greater than 3 months. Exclusion Criteria was patients with other chronic diseases including renal, cardiac, respiratory, hepatic or autoimmune disease, with Type 1 DM or less than 30 years old or diagnosed less than 3 months ago. Complete blood count parameters were recorded and analyzed. Results: Mean hemoglobin value was 11.5gm/dl. Hemoglobin was decreased in 121(59%). Out of 65 males the hemoglobin was decreased in 38(58.5%) and in 140 females decreased in 83(59.3%). (p=0.339). The TLC was increased in 50(24.4%), normal in 148(72.2%) and decreased in 7(3.4%). Among 65 males 11(16.9%), had increased TLC and in females in 39(27.9%). (p=.213). The platelet count is increased in 15(7.4%), normal in 173(84.8%) and decreased in 16(7.8%). In males the platelet count was increased in 2(3%), and in females in 13(9.4) (p=.180). Decreased hemoglobin and increased white cell count was highest in middle aged group. Microcytic anemia was common. There was a significant decrease in hemoglobin, an increase in white blood cell and platelet count in those on oral hypoglycemic in contrast to those on insulin or mixed therapy. Conclusion: Adult diabetics have a higher probability of having decreased hemoglobin and increased leucocyte count.