Hyperuricemia in metabolic syndrome.

Abstract

Objective: To determine frequency of hyperuricemia among the patients having metabolic syndrome. Study Design: Cross Sectional study. Setting: Indus Medical College, Tando Muhammad Khan. Period: 28-06-2021 till 28-12-2021. Material & Methods: After informed consent, 246 cases of metabolic syndrome who met the inclusion criteria were included. Inclusion criteria were the known case of metabolic syndrome for more than six months, of age group 20 to 60 years and of either gender. Exclusion criteria were the non-consenting patients as well as the patients with history of hyperthyroidism and hypothyroidism, gout, congestive cardiac failure, chronic renal failure, Post myocardial infarction, chronic liver disease, stroke, COPD & Pregnancy. Data analyzed on IBM SPSS 22.0 and p value< 0.05 taken as statistically significant. Results: Out of 246 patients mean age in our study was 40.80 years with the standard deviation of ±7. Mean FBS, triglycerides, HDL, SBP, DBP and waist circumference was 115.64±10.16 mg/dl, 144.7±10.43 mg/dl, 41.61±4.03 mg/dl, 168.5±4.16, 98.2±2.78 and 101±8.16 cm respectively. 93 (37.8%) were male and 153 (62.2%) were female. Out of 246 patients, 81 (32.9%) had hyperuricemia and 165 (67.1%) did not have hyperuricemia in patients with metabolic syndrome. Conclusion: This study concluded that hyperuricemia is 32.9% common in metabolic syndrome patients.