Plasma rich platelet efficacy in healing of chronic wounds.

Abstract

Objective: To determine the effect of platelets rich plasma in healing of chronic wounds. Introduction: In Medical specialties, The purpose of this study is to find out platelet growth factor from plasma rich platelet that could accelerate the spilt thickness of skin graft survival. Study Design: Randomized Control Trial. Settings: Medical Unit-I, Plastic Surgery Ward at Bahawal Victoria Hospital Bahawalpur in Collaboration with Pathology Department, Quaid-e-Azam Medical College, Bahawalpur. Period: January 2020 to July 2020. Material & Methods: In this study fifty patients of split thickness of skin graft were enrolled which having remain clinical reasons and Plasma rich platelet were collected by aphaeresis and applied immediately. PRP therapy was applied only on 30 patients while 20 patients were taken as standard control PRP was applied on 30 patients and followed them for 6 weeks. We start observation of PRP therapy from the 1^st dressing till the time of wound healing. Results: we have observed 100% up taken graft in patients who have received PRP therapy while in control group observed 4 patients showed complete graft loss 7 patients showed partial and 9 shoed complete uptake. Conclusion: This study demonstrated promising results to split thickness skin grafts by the application of Plasma rich platelets (PRP).