COPPER AND CADMIUM LEVELS IN HAIRS & NAILS;

An indicator of heavy metal pollution.

Authors

  • ASMA AYYUB B.Z.U. Multan, Pakistan.
  • MUHAMMAD. SHAKEEL AHMAD Nishter Medical College Multan, Pakistan.
  • NAHEED IKRAM B.Z.U. Multan. Pakistan.
  • Um-e-Ammara Shan B.Z.U. Multan. Pakistan.

DOI:

https://doi.org/10.29309/TPMJ/2013.20.02.626

Keywords:

Cu & Cd,, hair, nail, heavy metal pollution,, screening test.

Abstract

Heavy metals ingested or inhaled can affect liver, Brain, Bone and lungs. Raised copper and cadmium levels have been
seen in ischemic heart disease. A level of trace elements varies in blood among population. In this study Copper & Cadmium levels were
determined in hairs and nails; easy to sample and store. Purpose of this study is to find out relationships with heavy metals pollution and
try to develop as a screening test. Such work is not yet done in our population. 86 male subjects and 20 controls (male) were selected for
determination of Cu & Cad concentrations in hairs and nails. Medical history was noted. 3-4 fingernails and 1 tbsp of hair cut from the
nape of neck close to root were obtained. Samples were analyzed by atomic absorption spectrophotometer. Highly significant (p< 0.001)
raised copper levels were seen in hairs and nails of subjects (110.79+26.01 & 99.34 + 7.81μg/gm respectively) compared with control
(80.76+ 7.81& 77.65+ 2.48). Similarly significantly (p< 0.001) raised Cadmium levels were found in subjects (hairs 143.57+62.03&
nails 104.71+74.52) compared with control (89.20+ 12.98 & 77.54+ 12.32). Highly significant (p< 0.001) raised values of Cd & Cu
indicate that hairs and nails concentration may indicate heavy metals pollution & it can be easy sampling test for screening of pollution
about heavy metal exposure.

Author Biographies

ASMA AYYUB, B.Z.U. Multan, Pakistan.

MSc (Biochemistry) 
Department of Chemistry,

MUHAMMAD. SHAKEEL AHMAD, Nishter Medical College Multan, Pakistan.

Assistant professor Biochemistry

NAHEED IKRAM, B.Z.U. Multan. Pakistan.

Department of Chemistry,

Um-e-Ammara Shan, B.Z.U. Multan. Pakistan.

Department of Chemistry,

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Published

2013-02-07