Pre and postnatal assessment of gross parameters after utilization of high fat diet in rats.

Abstract

Objective: To assess the gross parameters of maternal weight and abdominal circumference upon utilization of high fat diet. Study Design: Experimental study. Setting: Al-Tibri Medical College and Hospital. Period: October 2019 to March 2020. Material & Methods: After taken an ethical approval total 16 female albino rats were selected and divided into two groups through randomized sampling and 2 male rats were introduced in each group for the purpose of mating, group A given a normal diet (control) and group B given a composition of high fat diet throughout the gestational period. The weights of the pregnant rats and the abdominal circumference were measured on day 1^st and 21^st of gestation. The data were analyzed through SPSS version 21.0, in the form of Mean ± standard deviation, and for the evaluation of level of significance independent “t” test was applied and considered value of significant was P=<0.05. Results: There was no significant difference in the weight or abdominal circumference of maternal rats in both groups. Conclusion: High fat diet having no significant effects on maternal weight and abdominal circumference as compared to normal diet. We need to assess other histomorphological parameters to assess the relative effects.