EFFECT OF CLARITHROMYCIN ON HEPATIC & RENAL FUNCTIONS

Authors

  • Muhammad Saeed Punjab Medical College, Faisalabad.
  • Shagufta Arif Govt College for Women (K.B), Faisalabad.
  • Muhammad Nawaz University of Agriculture Faisalabad.

DOI:

https://doi.org/10.29309/TPMJ/2001.8.01.5490

Abstract

OBJECTIVE: To evaluate the effects of clarithromycin on the hepatic and renal function in the adult male volunteers. SETTING: Shaffee Medical Centre, Faisalabad. PERIOD: May, 2000. METHOD: 14 young healthy volunteers were given 500 mg clarithromycin. Blood samples were taken before and after the drug intake. Serum Bilirubin, serum GPT (ALT), serum Alkaline phosphatase, serum Urea and creatinine were estimated. CONCLUSIONS: There was a significant change in the level of serum Alkaline phosphatase and creatinine levels after the intake of drug. The use of clarithromycin should be carefully monitored to avoid renal and hepatic dysfunctions.

Author Biographies

Muhammad Saeed, Punjab Medical College, Faisalabad.

Assoc. Professor of Biochemistry

Shagufta Arif, Govt College for Women (K.B), Faisalabad.

Asstt Professor of Chemistry,

Muhammad Nawaz, University of Agriculture Faisalabad.

Professor of Pharmacology,

Downloads

Published

2001-03-14

Issue

Vol. 8 No. 01 (2001): Vol 08 No 01

Section

Articles