SERUM LIPID PROFILE

THE EFFECTS OF DIETARY PUFA AND MUFA AN EXPERIMENTAL ANIMAL STUDY

Abstract

A diseases are the biggest threat to the life and health of adult people. Hyperlipidemia,
especially hypercholesterolemia is the strongest risk factor for atherosclerosis. Different types of dietary lipids have
been shown to affect the serum lipid profile differently. So dietary modification is a useful measure to treat
hyperlipidemia. In this study, effects of PUFA fat (corn oil) and MUFA fat (Olive oil) on serum lipid profile were
compared. We used albino rats as experimental animals. Thirty six albino rats of age 8 weeks were divided into three
groups of 12 each. They were fed diets containing different types of fat for 12 weeks. Serum lipid profile at 0 week
and 12 weeks were compared. It was seen that both PUFA diet and MUFA diet decreased all the serum lipid
fractions; PUFA diet was rather more potent in this regard. The only difference was in HDL-C fraction. HDL-C was
significantly decreased in case of PUFA diet while it was significantly increased in case of MUFA diet. So MUFA
diet is more advantageous for patients of atherosclerotic vascular diseases.