Correlation of C-reactive protein with stroke severity in patients with acute ischemic cerebrovascular stroke.

Abstract

Objective: To determine the correlation of mean serum C - reactive protein with frequency of stroke severity in patients with acute ischemic cerebrovascular stroke. Study Design: Descriptive Cross Sectional study. Setting: Department of Medicine, Allied Hospital Punjab Medical College Faisalabad. Period: March 2016 to September 2016 Material & Methods: Patients fulfilling the selection criteria were enrolled in the study. Besides routine laboratory tests, plasma CRP levels on admission were measured in all patients through hospital pathology laboratory. CRP levels were correlated with the results of NIHSS (National institute of health stroke scale) score based assessment of ischemic stroke severity at admission. Results: In our study, out of 50 cases of acute stroke, 62%(n=31) were male and 38%(n=19) were females, mean±sd for age was calculated as 46.82+8.65 years, mean CRP levels was calculated as 8.04+2.15mg/dL, mean NIHSS levels were calculated as 10.08+3. Correlation of mean serum C-reactive protein with frequency of stroke severity in patients with acute ischemic cerebrovascular stroke was calculated where r value was 0.9183 showing a strong positive correlation, which means that high CRP goes with high NIHSS (and vice versa). Conclusion: We concluded that CRP levels are positively correlated with the frequency of stroke severity in patients with acute ischemic cerebrovascular stroke.