PEUTZ JEGHERS SYNDROME

THE POLYP MAY BE MALIGNANT

Abstract

Peutz-Jegher’s syndrome is an uncommon disease. A case of 9 years old girl is presented who had signs and
symptoms of subacute intestinal obstruction. She had mucocutaneous pigmentation of mouth and lips as well.
Laparotomy revealed irreducible ileoileal intussusception with a polyp as lead point. Histopathological examination
of the polyp showed malignant change. The polyps of Peutz-Jegher’s syndrome had the reputation of being
hamartomas but lately, cases have been reported of malignant changes in them. Literature has been reviewed to
reassess the management of these cases due to increasing evidence of malignancy.