AZOOSPERMIA & OLIGOZOOSPERMIA

SEMEN AND HORMONAL ANALYSIS OF PATIENTS

Authors

  • MUBASHIR. A. SHEIKH Jinnah Postgraduate Medical center, Karachi
  • Bilquees Begum Jinnah Postgraduate Medical center Karachi
  • MUHAMMAD SHOAIB KHAN Islamabad
  • Aftab Turabi Jinnah Postgraduate Medical center Karachi
  • AHMED DANYAL Nishtar Medical College, Multan
  • S. Saud Hasan Zaidi Dow University of Health Sciences Karachi

DOI:

https://doi.org/10.29309/TPMJ/2005.12.01.5170

Keywords:

Azoospermia, Oligozoospermia, Asthenozoospermia, LH, FSH, Prolactin, testosterone, Infertile, Male, Pakistan

Abstract

Objectives: To differentiate and analyses different groups of patients
according to abnormalities of azoospermia and oligozoospermia. Design of study: Prospective study Setting: Clinical
pathology Laboratory Jinnah Postgraduate Medical Centre Karachi. Period: 1999 to2003. Material & Method:
Analysis of semen volume, liquefaction time, pH and sperm concentration were carried out for 150 men from infertile
couples alongwith measurement of hormone levels. 50 normal fathers with proven fertility were taken as control.
Results: 33.33% patients showed azoospermia (A), 50 cases (33.33%) had oligozoospermia (B), 20 cases (13.33%)
were asthenozoospermic (C) and 30 cases (20%) were found to be normozoospermic (D). The hormonal profile
showed normal or low levels of testosterone while FSH and LH levels indicated inverse/negative correlation to sperm
concentration, whereas no significant relationship between serum prolactin and semen density was detectable between
different groups. Conclusions: Azoospermic and oligozoospermic subjects are accompanied by a significant rise in
FSH levels, and decrease in serum testosterone level. The need for measuring prolactin levels in the evaluation of male
infertility is unnecessary.

Author Biographies

MUBASHIR. A. SHEIKH, Jinnah Postgraduate Medical center, Karachi

Department of Clinical Pathology

Bilquees Begum, Jinnah Postgraduate Medical center Karachi

Department of Clinical Pathology

MUHAMMAD SHOAIB KHAN, Islamabad

Scientific Officer NIH

Aftab Turabi, Jinnah Postgraduate Medical center Karachi

Department of Clinical Pathology

AHMED DANYAL, Nishtar Medical College, Multan

Assistant Professor of Pharmacology

S. Saud Hasan Zaidi, Dow University of Health Sciences Karachi

Pharmacology & Therapeutics

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Published

2005-03-25