URINARY TRACT INFECTION

AN OLD DISEASE IN THE NEW AGE

Abstract

Objectives: To document the common microorganisms causing UTI in human
and their resistance to currently used antibiotics. Data Source: PMRC, Research Center Khyber Medical College
Peshawar Design: Retrospective analytical study. Period: Jan 2000 to June 2003. Material and Methods: Evaluation
results of 597 urine cultures performed during the period, on clinically suspected referred subjects. Results: Bacterial
growth was obtained in 35% samples. Common micro organisms in decreasing order of yield are E. Coli, Klebsiella,
Staph aureus, Proteus species and pseudomonas isolated from 80, 7.1, 5. & 1.5% samples respectively. 100%
sensitivity is observed for imipenum. Efficacy next in decreasing order was for Amikacin, Tarivid, Ciproxin and
Rocephin. Conclusion: Esch. Coli is the predominant etiological organism of UTI and imipenum is the drug of choice
to which over 80% of all the different organisms are sensitive. Recommendation: Constantly changing sensitivity
pattern of the organisms responsible for UTI demands a periodic check for better selection of drug and reduction of
consequences of the disease.