HEPATITIS G VIRUS

REPLICATION SITES DETECTION IN DIFFERENT HUMAN TISSUES

Authors

  • NASIR MAHMOOD School of Biological Sciences, Quaid-e-Azam campus, University of the Punjab, Lahore, Pakistan
  • MUZAFFAR JALAL KHAN King Edward Medical College, Lahore, Pakistan.
  • NASEER AHMAD Distric Health Development Center (DHDC), Health Department, Jhelum., Pakistan.

DOI:

https://doi.org/10.29309/TPMJ/2005.12.02.5139

Abstract

The total forty five samples were tested for the presence of hepatitis G virus
(HGV) positive (genomic) and negative (replicative) strand by RT-PCR. These samples were divided into three groups
containing 15 each. Group I contained blood samples only, group II had blood samples along bone marrow samples
of the same patients and group III contained different tissue samples collected from autopsy cases. In group I no
sample was found out to be HGV positive while in group II 6.66 % samples were HGV positive and replicative strand
was detected only in bone marrow tissue. In group III, 13.33 % samples were found to be HGV positive and in two
positive samples of group III, replicative strand was detected in blood, bone marrow and spleen tissue. These results
suggested that blood, bone marrow and spleen are the major replication sites of hepatitis G virus.

Author Biographies

MUZAFFAR JALAL KHAN, King Edward Medical College, Lahore, Pakistan.

Professor of Anatomy (Retd.),

NASEER AHMAD, Distric Health Development Center (DHDC), Health Department, Jhelum., Pakistan.

Programme Director,

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Published

2005-06-25

Issue

Vol. 12 No. 02 (2005): Vol 12 No 02

Section

Articles