LARYNGOSCOPY AND TRACHEAL INTUBATION

EFFICACY OF IV LIGNOCAINE IN ATTENUATING HEMODYNAMIC RESPONSES

Abstract

Objectives: To assess the efficacy of IV Lignocaine in a dose of 1.5 mg/kg
to attenuate the haemodynemic response of laryngoscopy and tracheal intubation. Design of study: A control
interventional prospective study. Setting: CMH Gujranwala and CMH Muzaffarabad. Period: Jan 2004 to Dec 2004.
Method & materials: 120 ASA I & II patients anaesthetized with thiopentone sodium and suxamethomium. Patients
were allocated randomly to a control group or three treatment groups to receive lignocaine 1.5 mg/kg I. V, 3,2, minutes
respectively before laryngoscopy. Results: Maximum increase in heart rate was 1 minute after laryngoscopy and
intubation in all four groups (21-30%). There was no significant difference between the groups. Maximum rise in MAP
was also 1 minute after laryngoscopy and intubation averaging 31.2%, 25%, 26.9%, 26.4% in group I, II, II, IV
respectively. There was no significant (P>.05) difference in the rise of mean arterial pressure(MAP) in patients receiving
IV lignocaine when compared with the control group. Conclusions: IV lignocaine in a dose of 1.5 mg/kg starting 3
minutes before laryngoscopy and intubation does not suppresses significantly, the increase in MAP and heart rate ,
during laryngoscopy and endotracheal intubation.