HEPATITIS B & C;

FREQUENCY OF VIRAL INFECTION IN SURGICAL PATIENTS

Abstract

Objectives: To determine the frequency of hepatitis b & c viral infection in
surgical patients. Study Design: Descriptive case series. Place and Duration of Study: This
study was conducted at surgical department of multiple hospitals and compares the results,
JPMC Karachi, Civil Hospital Naushahro Feroze and Jamshoro, Pakistan from August 2014 to
December 2015. Methodology: All 2645 patients were admitted for emergency and elective
surgery. All patients taken detail history regarding demographic parameter and risk factors
like previous surgery, blood transfusion, barbar, Road Traffic accident, haemodialysis, Tattoos/
body piercing, injecting drug user, family history of hepatitis, previous history of jaundice
and Hospitalization. Hospital laboratory was used for screened HBsAg and Anti HCV using
immunochromatography (ICT method). Patients excluded who were those did not need the
surgery or known case of HBsAg and Anti HCV. Data collected was entered into and analyzed
by using statistical package for the social science – 20. Results: Out of 2645 patients, male
to female ratio were 1.9:1. The mean age was 40.2+6.12years (20 to 60 years). Out of 2645
patients, Anti HCV was positive in 288(10.88%) cases followed by HBsAg was in 152(5.74%)
cases. While both positive in 36 (1.36%) cases. We observed Previous surgery was main risk
factor in the reactive 156(32.77%) cases followed by Barbar, Blood transfusion were 74(15.54%)
and 47(9.87%) respectively. Conclusion: We conclude that preoperatively screening of hepatitis
B and C should be performed.