SERUM SIALIC ACID CONCENTRATION AND TYPE II DIABETES MELLITUS

Authors

  • MOHAMMAD JAWAID SABZWARI jawaidsubzwari@hotmail.com
  • MUKHTAR AHMAD jawaidsubzwari@hotmail.com
  • MUHAMMAD TAHIR MAJEED Postgraduate Medical Institute, Shaikh Zayed Medical Complex, Lahore.
  • Muhammad Riaz Fatima Memorial Medical and Dental College, Shadman, Lahore.
  • Muhammad Umair Fatima Memorial Medical and Dental College, Shadman, Lahore.

DOI:

https://doi.org/10.29309/TPMJ/2006.13.04.4913

Keywords:

Sialic acid, Type II diabetes mellitus, Blood glucose

Abstract

Sialic Acid (SA) is an acetylated product of neuraminic acid. In present
study, the relationship between sialic acid and type II diabetic patients was investigated. Ninety (90) subjects, 41 males
and 49 females, were included in the study. They were divided into two groups according to presence or absence of
type II diabetes mellitus (DM). Group A comprised of 72 patients with type II DM and group B 18 subjects without
diabetes mellitus as a control group. The following parameters were assessed: sialic acid, blood glucose, lipid profile
(serum triglycerides and total cholesterol) and HbA1c. Type II DM Patients had higher levels (P<0.05) of sialic acid
(2.259±0.252 mmol/L) as compared to the control group (2.048±0.32 mmol/L).

Author Biographies

MOHAMMAD JAWAID SABZWARI, jawaidsubzwari@hotmail.com

Assistant Professor (Chemical Pathology),

MUKHTAR AHMAD, jawaidsubzwari@hotmail.com

Assistant Professor of Biochemistry,

MUHAMMAD TAHIR MAJEED, Postgraduate Medical Institute, Shaikh Zayed Medical Complex, Lahore.

Microbiology Department, Federal

Muhammad Riaz, Fatima Memorial Medical and Dental College, Shadman, Lahore.

M.B., B.S

Muhammad Umair, Fatima Memorial Medical and Dental College, Shadman, Lahore.

3rd Year M.B.B.S Student

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Published

2006-12-16