CHRONIC SUPPURATIVE OTITIS MEDIA

FREQUENCY OF PSEUDOMONAS AERUGINOSA IN PATIENTS AND ITS SENSITIVITY TO VARIOUS ANTIBIOTICS.

Abstract

Objectives: To identify the frequency of pseudomonas aeruginosa in
patients of chronic suppurative otitis media and it sensitivity to various antibiotics. Design: A descriptive study. Place
& Duration of Study: The study was carried out from Nov 2002 to may 2003 at Department of ENT, Head and Neck
surgery, Combined Military Hospital, Rawalpindi. Material & Methods: A total 150 patients with unilateral or bilateral
active Chronic Suppurative Otitis Media from the out patients clinic were included in the study. All patients were
evaluated through detailed history and through clinical examination. Pus samples were collected from the discharging
ear(s) and sent to pathological laboratory of the hospital for culture sensitivity. Results: In this study, 82% cases
yielded pure cultures, 15% yielded mixed cultures while 3% yielded no growth. The pure cultures yielded pseudomonas
aeruginosa in 52.5% of the cases, Staph. Aureus in 15%, Proteus SPP in 6.5%, klebsiella in 2.6%, E. Coli in 2%,
anaerobes in 1.3%, Aspergillus in 1.3% and Candida in 0.6% of the cases. In mixed cultures, pseudomonas was
isolated in 7.3% of the cases, Staph. Aureus in 2.6%, proteus in 2%, Klebsiella in 0.6% and E. Coli in 0.6% of the
cases. Pseudomonas was sensitive to Gentamicin in 70% of cases, Amikacin 92%, Ciprofloxacin 95%, Ceftazidime
84%, Cephoperazone 82%, Cefipime 84%, Aztreonam 83%, imipenem 98%, Levofloxacin 97%, Augmentin 67% and
chloramphenicol in 56% of the cases. Conclusion: Pseudomonas aeruginosa was the most commonly isolated
organism followed by staphylococcus aureus. Pseudomonas aeruginosa is increasingly becoming more resistant to
the common dugs. This necessitates the early diagnosis and prompt treatment of the disease so as to avoid the
complications of CSOM.