PRE-EMPTIVE PAIN CONTROL

COMPARISON OF KETOROLAC AND DICLOFENAC SODIUM

Abstract

Introduction: Opioid related side effects have encouraged the use of analgesic drugs that are devoid
of these problems. Objective:- This study was done to compare the analgesic efficacy of Ketorolac and diclofenac
in 60 adult patients of age group ranging between 30 to 45 years of age body wt 50-60kg belonging to ASA I and II
grade. Material and Methods: Patients were scheduled for elective gynecological procedure (laparoscopic tubal
ligation) under general anaesthesia. They were divided into two equal groups using non-probability convenience
sampling technique. Each group comprised of 30 patients. Group A received Ketorolac 10 mg I/V with local infiltration
of 0.5% Bupivacaine and group B received IM Diclofenac sodium 75 mg after local infiltration 0.5% bupivacaine as
in Group A ½ hourly before surgery. Post operatively patients were observed after 30 minutes in the recovery room
for pain relief for two hours. Mean pain scores were noted in the recovery area using visual analog scale with need for
supplementary analgesic after awakening from general anaesthesia. Vital signs were monitored. Result: Results were
analyzed by using SPSS-8 package by applying Student Test and chi Square Test. There was statistically significant
difference between two groups regarding their mean pain score. Conclusion: The patients who received Ketorolac
I/V (Group A) had longer pain free time interval and request for first analgesic supplement was made after 90 minutes
compared to a shorter interval of 60 minutes in Group-B, who received intramuscular diclofenac sodium.