A possible linkage between low density lipoproteins and ischemic stroke.

Abstract

Objective: To determine the frequency of raised low density lipoproteins (LDL) in subjects with ischemic stroke (IS) in our local population. Study Design: Cross-sectional study. Setting: Medical Unit-III, Nishtar Medical College, Multan. Period: 12 March 2016 to 12 September 2016. Material & Methods: Eligibility criteria include subjects with age limit between 40-70 year of both sex surfing with ischemic stroke. Raised-LDL means serum fasting LDL level ≥ 100 mg/dl was deemed as raised LDL on two different reading 24 hours apart (both was raised). Results: Our study registered a total of 205 patients out of this 92 (44.9%) were male patients while 113 (55.1%) were female with ischemic stroke. Mean height and weight of our study cases was 159.94 ± 11.21 and 68.43 ± 6.33 respectively. Mean BMI was noted to be 23.17± 2.85 kg/m². Mean LDL level noted in our study was 109.59 ± 49.15 mg/dl and raised level of LDL was seen in 88 (42.9%) of our study cases. Raised level of LDL was observed significant in gender, diabetes, obesity, hypertension, family history and previous history of stoke. Conclusion: Very high frequency of raised serum LDL levels was noted in our study. Raised LDL were positively linked with male gender, hypertension, family history of stroke, diabetes, obesity and past event of stroke. Our study determines the initial diagnosis of stoke that eventually lead to suitable management to enhance clinical result in such subjects.