Association of hypovitaminosis D with poor glycemic control and obesity in type II diabetes mellitus.

Abstract

Objectives: To determine the association of low serum vitamin D levels with poor glycemic control and obesity in type 2 diabetic patients. Study Design: Descriptive Cross Sectional study. Setting: Sakina Institute of Diabetes and Endocrine Research Centre (SIDER), Shalamar Hospital Lahore. Period: 1^st June to 31^th august 2017. Material & Methods: After applying strict exclusion criteria, about 450 patients with known type II diabetes were enrolled in the present study and their HBA1C and fasting vitamin D levels were measured. Patients were divided into two groups, group 1 with poor glycemic control (HBA1C>8%) and group 2 with good glycemic control (HBA1C <8%). Results: After performing extensive matching in both groups, it was found that vitamin D levels in group 1 with poor glycemic control were significantly low as compared to group 2 with good glycemic control (p value <0.001). Furthermore, approximately 87% of patients with BMI >23 were having suboptimal Vitamin D levels (p value <0.005). Conclusions: Low serum vitamin D is associated with poor glycemic control in type 2 diabetics and vitamin d supplementation could possibly play a role in improving glycemic control in these patients. Furthermore, hypovitaminosis D is also associated with obesity.