EFFICACY OF ANTICHLONERGIC DRUGS IN IDIOPATHIC OVERACTIVE BLADDER.

Abstract

Background: Symptoms of overactive bladder include urgency, frequency, and urge incontinence, with or without noctiuria. Symptoms are common in adults. The two main treatment options for overactive bladder syndrome are bladder retraining and anticholinergic drugs. Study Design: Cross sectional study. Setting: Urology Department, Kot Khawaja Saeed Hospital, Lahore. Period: January to June 2017. Methodology: Eighty patients were enrolled after informed consent. All patients were subjected to 5mg solifenacin succinate for three months. International Consultation on Incontinence Questionnaire-Urinary Incontinence (ICIQ-UI) was utilized to assess patient symptoms. Results: There 56 males (70%) and 24 female (30%) with mean age of 43 ± 1.6 years. Efficacy of solifenacin was found in 61 cases out of 80 patients. On first visit 19 (31%) patients were cured, 17 (28%) on second month follow up and 25 (41%) were cured on third month follow up. Conclusion: Solifenacin has significant role in managing patients with overactive bladder. It has a relatively safe side effect profile.