ROLE OF LIPOPROTEINS IN MYOCARDIAL INFARCTION

Abstract

Coronary Heart Disease (CHD) is the foremost cause of death in women as well as in men, although the onset of the CHD is earlier on the average in men. Objective: The aim of this study was the evaluation of serum lipids and lipoproteins levels in male and female survivor of first attack of myocardial infarction of various age groups. Place and duration of study: cardiology ward at B.V.H. Bahawalpur 1989 to 1990. Materials and Methods: A total number of 128 patients of myocardial infarction (108 males, 20 females) were selected for study from those who were admitted in coronary care unit. Serum lipids, lipoproteins, relative body weight and blood pressure were assessed in 108 male and 20 female survivors
of first attack of myocardial infarction of various age groups. Results: The majority of patients fall in middle aged category. The mean age and weights were almost similar for patient groups and controls. Generally, there was a significant rise in the mean values of blood pressure, serum cholesterol, triglyceride, VLDL and LDL. The patients of various age groups were also found to have significantly higher levels of VLDLcholesterol,
LDL cholesterol and significantly lower levels of HDL-cholesterol than those of control groups Conclusion: HDL-C can be inferred as a marker or predictor of risk of CHD in woman .It has an inverse association with the incidence of CHD in both men and women. It was also conclusion in patients with acute myocardial infarction age was a powerful independent predictor of in-hospital mortality and complications. Suggestion: It is suggested that work may be extended by the comparative study of Troponin with Myoglobin. Which may be used as marker for acute myocardial.