Case Report: Rare case of classical Hodgkin’s lymphoma, mixed cellularity in a male boy aged 12 years.

Abstract

Castleman disease was initially explained in 1956 as a syndrome that is lymphoproliferative, also recognized as angiofollicular lymph node hyperplasia. It is a rare disease and may proceed to malignant lymphoma that is difficult to diagnose while the treatment is complex. Hodgkin lymphoma (HL) is a malignancy that is related to lymphoid and can be characterized as Reed-Sternberg cells in the lymph nodes. Prognosis as well as treatment is complex and depends upon the Ann Arbor staging as well as age of the affected patient. HL is divided into 2 distinct subtypes, Nodular Lymphocyte Predominant HL (LPHL), and classical HL (cHL). The present case was a 12year old male boy who presented with fever, cough and swelling on the body at multiple sites. Diagnosis of cervical lymph node biopsy was labeled as classical Hodgkin’s Lymphoma, mixed cellularity. Early diagnosis, better understanding of the pathophysiology as well as the biology of HL can assure much better prognosis.