Risk factors and fetomaternal outcome in pregnancy with thrombocytopenia.

Abstract

Objectives: To find out the risk factors and their effects on mother and fetus in pregnancy with thrombocytopenia. Study Design: Cross sectional study. Setting: Department of Obstetrics and Gynaecology at Liaquat University Hospital Hyderabad. Period: Six months (1st July 2016 to 31st December 2016). Material and Methods: Total 96 patients with gestational age >24 weeks having platelet count below 150X109/L were included in the study. Patients admitted throughout patient clinic department of obstetrics & Gynecology at Liaqat University Hospital. Those patients having platelet count below 150X10⁹/L were registered for study. Proforma filled which include Patients demographics details, gestational age, complete blood count (Having platelet count) other important investigations like coagulation profile (PT, APTT), Ultrasound and LFT noted in proforma SPSS version used for analysis. Descriptive statics were calculated frequency and percentages were drawn for the study. Results: Risk factors related to thrombocytopenia included PIH18 (18.8%), preeclampsia 14(14.6%), eclampsia 10(10.3%), HELLP Syndrome 6(6.3%), Viral Hepatitis 12(12.5%) and in 36(37.5%) no risk factors was found. Maternal complication were placental abruption21 (21.8%) post partam hemorrhage 14(14.6%). 7(7.3%) were transferred to ICU and 02(2.1%) maternal death was seen. Fetal outcome include low Apgar score of <6 in 17(17.7%), low birth weight 16(16.7%) and NICU admission 11(11.5%). Conclusion: Thrombocytopenia is a common finding in pregnancy careful diagnosis is important to distinguish serious causes from mild then to manage mother and fetus appropriately. Thrombocytopenia in pregnancy is associated with adverse maternal and fetal outcome in significant number of pregnant woman.