HEAVY SMOKING

Abstract

Objective: This study is conducted to observe the serum lipoprotein alterations in chronic heavy smokers in LUMHS Sindh. Study Design: Analytical study Material and Methods: It was conducted on 60 non obese adult smokers, both sexes, who smoked more than twenty cigarettes or beeries a day regularly for more than five years. All the participants were current smokers. Sampling technique was simple random technique. Setting: The study was conducted in outdoor department of LUMHS Jamshoro/Hyderabad. Period: Jan 2010 to Jan 2011. Eighteen hours fasting blood sample was sent for lipid studies. Lipids studied were serum cholesterol, serum triglycerides, high density lipoproteins and low density lipoproteins. For control values ATP 3 guidelines were used. Statistics: Mean of statistical values was calculated with standard deviation and variance in standard deviation. Results obtained were analyzed by SPSS 11. Results: Age of the patients was 25-70 years. Mean age was 47.81±12.96 years. Median age was 50 years. Male/ female ratio was 45/15. Patients were from both rural and urban areas. Mean duration of smoking was 25.5±9.15 years. The study carried out on 60 chronic heavy smokers, showed deranged lipid levels as: Total cholesterol mean 237.57 mg/dl ±37.89; TG mean 203.76 mg/dl ±47.08; LDL-C mean 158.62 mg/dl ±17.25; HDL-C mean 29.67 mg/dl ±3.12. Results are shown in Table No I. Conclusions: Our study concluded at LUMHS showed that by continuous heavy smoking the serum lipid levels get deranged.