HELICOBACTER PYLORI

PATIENTS WITH FUNCTIONAL DYSPEPSIA

Abstract

Objective: To determine the frequency of H. pylori in patients with functional
dyspepsia. Patients and methods: This six months multidisciplinary study was conducted at
tertiary care teaching hospital as well as at private hospital Hyderabad from February 2012 to July
2012. All patients presented with history of dyspepsia were admitted and evaluated for functional
dyspepsia by performing endoscopy. After confirmation of functional dyspepsia the subjects
were further evaluated for H. pylori infection by taking the biopsy specimen, label it and sent to
laboratory for histopathological examination. The data was entered, saved and analyzed in SPSS
version 11.00. Results: During six month study period, total 100 patients with functional
dyspepsia were recruited. Majority of patients were from low socioeconomic class (78%), have
history of spicy food intake (68%) and epigastric pain (94%). The associated symptoms observed
were nausea and vomiting (87%), anorexia (88%), early satiety (84%) and regurgitation (84%).
The mean ±SD for age of patients with functional dyspepsia was 37.95±10.85. The mean age
±SD of H. pylori identified patients was 35.81±7.72. Majority of the subjects was 30-40 years of
age and the male population predominant 64% (p-value 0.02, statistically significant). The H.
pylori was identified in 62% of patients, of which 35 (56.5%) were males and 27(43.5%) were
females (p-value 0.04, statistically significant) respectively.