UNILATERAL SPINAL ANAESTHESIA

ADDITION OF PETHIDINE TO BPIVACAINE FOR PAIN RELIEF IN HIP SURGERY

Abstract

Objectives: To see the effects of adding pethidine to intrathecal bupivacaine on duration of post operative analgesia in
patients undergoing hip surgery. Design: A randomized placebo controlled observational study. Setting C M H Multan: Period: From March
2006 to April 2007. Patient and Methods: A total of 90 male patients of age 60-75 years of comparable weight and height and ASA
status II, III were selected. Patients were divided into two groups, group A and group B. Each group consisted of 45 patients. All patients were
assessed pre operatively a day before surgery and were briefed about the procedure. Results: All the patients were prepared before giving
spinal anaesthesia. Patients in Group- A were given a mixture 01 ml of 0.75 bupivacaine and 0.2 ml of normal saline in lateral decubitus position
with operating side down by using 23 G spinal needle. Patients in Group-B were given a mixture of 01 ml of 0.75 % bupivacaine and 0.2 ml
of inj. pethidine 10mg in lateral decubitus position with operating side down by using 23 G spinal needle. All the patients were kept in lateral
decubitus position for 10 minutes to achieve unilateral block. Intra operative adverse effects like hypotension, nausea, vomiting, pruritis and
delayed respiratory depression and effective duration of post operative analgesia was recorded. Conclusion Addition of 10 mg pethidine to
intrathecal hyperbaric bupivacaine is associated with prolonged postoperative analgesia and minimal side effects like hypotension, pruritis, and
delayed respiratory depression. However incidence of nausea and vomiting was much more