DIABETES MELLITUS;

PREVALENCE IN PATIENTS OF CHRONIC HEPATITIS C

Abstract

Objective: To determine the prevalence of Diabetes mellitus in patients of hepatitis C virus infection. Design: Prospective and
observational study. Setting: Medical Wards at Combined Military Hospital Jhelum. Period: 1st November 2009 to 31st October 2010. Method:
100 cases of HCV positive on Elisa method were inducted. All cases were segregated into different states of liver disorders and were screened
for Blood Sugar level, for one year. So as to observe the frequency of Diabetes Mellitus among HCV positive patients. Diabetes mellitus was
considered to be present if patients were already on diabetes treatment or fasting or random blood sugar indicated diabetes mellitus according
to standard criteria. Results: One hundred patients were studied. Fifty five (55 %) were males and forty five (45 %) were females. The ages
ranged from 15 to 71 years (Mean 44.24). Out of these 100 patients, total of 28 (28%) had diabetes mellitus. Out of 100 patients, 82 patients had
chronic hepatitis C virus infection without cirrhosis and 22 (26.4 %) of these had diabetes. Twenty two patients with chronic hepatitis C, who had
diabetes mellitus, twenty (90.9 %) were non-insulin dependent diabetics and two (9.1 %) were insulin dependent. Total of 18 patients had
cirrhosis and out of these 6 patients (33.33 %) had diabetes mellitus. Six patients with cirrhosis all had non-insulin dependent diabetes mellitus.
Conclusions: Patient with chronic hepatitis C virus infection and cirrhosis secondary to hepatitis C virus infection have strong association with
diabetes mellitus and great majority of them are non-insulin dependent diabetics.