POLYCYSTIC OVARIAN SYNDROME

PATTERN OF DISEASE IN PATIENTS

Abstract

Objectives: The objective of this study is to: describe the pattern of disease in
patients with polycystic ovarian syndrome. Data Source: Medline Data Base. Design Of Study:
Descriptive case series study. Settings: Gynaecological Outpatient Department of Ghurki trust
teaching hospital Lahore. Duration: 6months period, from 8th October 2012 to 7th April 2013.
Materials & Methods: Sixty cases of polycystic ovarian syndrome as diagnosed on ultrasound
were selected. These cases were examined for height, weight, body mass index, hirsutism, acne,
acnthosis nigricans, breast examination (galactorrhoea). These cases were investigated for
blood sugar (random), Fasting Insulin, pelvic ultrasound, LH, FSH and serum prolactin. Results:
The mean age of the patients were 24.93±5.67 years. There were 28 (47%) patients of menstrual
disturbance, 18 (30%) patients of subfertility, 9 (13%) of obesity. There were 13 (21.7%) patients
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of BMI level of equal to or less than 25 kg/m and 47 (78.3%) patients of BMI level more than 25
2
kg/m . There were 25 (41.7%) patients of hirsuitim, 14 (23.3%) patients of acne and 17 (28.3%)
patients of acanthoris nigricans on physical examination. There were 28 (46.7%) patients of LH
level of more than 10 IU/L (raised) and 1 (1.7%) patient of more than 350 mU/L prolactin (raised).
The mean right ovary volume of the patients was 12.08±3.04 and mean left ovarian volume of the
patients was 11.86±4.83. Conclusions: Hirsutism and cycle disturbances are the major clinical
features of polycystic ovarian syndrome patients. Obesity seems to be more prevalent in
polycystic ovarian syndrome patients. The ratio between LH and FSH as a diagnostic tool was
low in our patients.