PTERYGIUM

COMPARISON OF RESULTS EXCISION THROUGH BARE SCLERA TECHNIQUE WITH AND WITHOUT INTRAOPERATIVE MITOMYCIN C APPLICATION

Abstract

Objective: To study the results of primary pterygium excision through bare sclera
technique with and without intraoperative Mitomycin C use. Study design: This was an
experimental study with randomised controlled trial. Setting and Duration: This study was
conducted at Eye A unit, Khyber Teaching Hospital, Peshawar from May,2007 to April,2009.
Methodology: One hundred patients with primary pterygium were selected from ophthalmology
Deptt. OPD at Khyber Teaching Hospital, Peshawar. Detailed history was taken. Complete ocular
examination done and those fulfilling inclusion criteria were included in the study. Anesthesia
used was topical proparacaine 0.5% and local infiltration of 2% lignocaine. Mitomycine C (MMC)
0.02% (0.2mg/ml) was applied through a cotton swab at the bare part of the sclera for five minutes
in 50 of these patients. Patients were followed up till three months. Results: In bare sclera
technique without MMC, recurrence rate was 70% (35 patients) while in MMC group, it was 16%
(08 patients).There was one punctuate epithelial keratitis in MMC group and two cases of
conjuntival granuloma one in each group. Conclusions: Pterygium excision through simple
bare sclera technique had significantly high recurrence rate as compared to intraoperative use of
MMC.