COMMON HUMAN PATHOGENS

ANTIMICROBIAL ROLE OF GINGER (ZINGIBER OFFICINALE)

Abstract

Background: Due to easy availability or excess to antibiotics people usually
start antibiotic without consulting doctors when they are suffering from illness and as they were
feeling well they discontinue the treatment and as a result these bacteria become resistant
to those antibiotics which are inadequately used. Also most of the antibiotic have side effect
that also produce undesirable effect so after considering all of these issues we want to
explore natural compounds for their antimicrobial activity as these compounds have no side
effect and cost effective as well. Objectives: We analyzed the antimicrobial activity of ginger
(ZINGIBER OFFICINALE) against common human pathogens. Study design: Experimental
study. Place and duration of study: All clinical isolates were identified at BUMDC (Bahria
University Medical and Dental College) Microbiology Lab (Karachi) by standard biochemical
methods. Study conducted between april2015-nov 2015. Material & Methods: Staphylococcus
aureus, Pseudomonas, Vibrio cholera and E.Coli culture sample were taken and again
characterized using conventional biochemical, cultural and molecular methods. Then I checked
the antimicrobial activity of ginger alone and with soyaoil against these isolates using disc
diffusion method. Result: It shows that ginger alone having good antimicrobial activity against
pseudomonas but when using after mixing with soya oil its antimicrobial activity decreased
as it was note when individually used. Conclusion: Ginger when using alone having good
antimicrobial activity then when using in combination with soya.