ASYMPTOMATIC DIABETICS

DIASTOLIC DYSFUNCTION

Abstract

Background: Diabetes mellitus (DM) is not only a significant independent risk
factor for developing of atherosclerotic ischemic heart disease or ventricular hypertrophy but it
is also able to trigger a diabetic cardiomyopathy due to dysmetabolic processes resulting heart
failure. Cardiovascular complications are known to be the main cause of death and morbidity in
diabetic patients. Objectives: How frequent is the diastolic dysfunction in asymptomatic diabetic?
Study Design: Descriptive cross sectional. Setting: Echocardiography department Faisalabad
Institute of Cardiology Faisalabad. Patients were recruited from outpatient department of
Faisalabad institute of cardiology Faisalabad. Duration of Study: Six months from: 28-06-2015
to 28-12-2015. Methodology: 200 patients were included in the study. Patient’s bio data was
recorded and informed consent was taken. All echocardiographic studies were performed with
VIVID-07 echo machine by the same operator. Detailed assessment of left ventricular systolic
and diastolic function by using standard 2-dimensional, color flow Doppler and tissue Doppler
imaging (TDI) was done. Images were obtained in all patients. Each patient underwent left
ventricular (LV) diastolic function assessment by conventional Doppler, tissue Doppler imaging
(TDI). LV ejection fraction was calculated using conventional method. Blood flow velocities at
mitral valve leaflets and pulmonary veins were recorded with averaged from 3 end-expiratory
cycles at a sweep of 100 mm/s. This information was collected through a specially designed
proforma by the author. Results: In our study, out of 200 cases, 52%(n=104) were between 50-
55 years of age while 48%(n=96) were between 56-60 years of age, mean+sd was calculated
as 55.54+2.59 years, 49%(n=98) were male while 51%(n=102) were females, frequency of
diastolic dysfunction in asymptomatic, normotensive patients with diabetes mellitus was
recorded as 45.5%(n=91) while 54.5%(n=109) had no findings of the morbidity. Conclusion:
We conclude that the frequency of diastolic dysfunction is quite high (45.5%) in asymptomatic
diabetics.