PRIMARY NEUROENDOCRINE TUMORS

Abstract

Objective: To evaluate clinical presentation and surgical out come of primary neuroendocrine tumors of Kidney, U. bladder
and Prostate gland. Design: A Retrospective study. Setting: Urology Department, SMBBMU Larkana. Period: 2001-2011. Patients and
Methods: Series of 6 patients of primary neuroendocrine tumors of Kidney, U. bladder and Prostate gland were identified from 1890
cases of urinary tract tumors. Two cases of renal carcinoid, two cases of small cell carcinoma of urinary bladder and two cases of small
cell carcinoma of prostate glands. Renal carcinoid tumors presenting with lumbar pain and microscopic haematuria and identified on the
ultrasound. Small cell carcinoma of urinary bladder presenting with dysuria, gross haematuria and on ultrasound while small cell
carcinoma of prostate gland presenting with irritatory and obstructive symptoms and confirmed on DRE. Results: 6 patients(5 male and
1 female),Mean age of patients were 45years and range was 35-55 years. All patients treated primarily by definitive surgery like Radical
Nephrectomy, TURBT and Pallitive TURP and all tumors confirmed on histopathological examination and referred to LINAR Larkana for
proper managements. Conclusions: primary neuroendocrine tumors of Kidney, U.bladder and Prostate gland are rare tumors. Carcinoid
tumors have good prognosis but small cell carcinoma have poor prognosis so require prompt treatment.