NASAL POLYPS

IN FUNGAL NASAL POLYPS DETERMINE INVOLVEMENT OF FUNGUS TYPE

Abstract

Background: Nasal polyposis is a provocative situation of indefinite etiology that
involve nasal as well as sinus mucous membrane. Quality of life of a person can damage by nasal
impediment due to these nasal polyps. Further, it can cause of persistent postnasal drainage,
hyposmia, sinusitis, taste sense change even bony demolition. It shows that inflammation
reason a reactive hyperplasia of intra-nasal mucosal membrane resulted in the polyp formation.
Objectives: To discover the kind of fungus concerned in nasal polyps fungal. Study Design:
Descriptive study. Setting: ENT department of Sir Ganga Ram Hospital Lahore. Period: 1st
January 2017 to 30th June 2017. Materials and Methods: In microbiology department, these
collected samples were processed to check the involvement of fungal. Out of all, 118 cases
were included in this study which culture was positive. Increase for microscopic assessment,
mycological culture to determine the involvement of fungal and fungus kind, these samples
were processed for diagnosis by potassium hydroxide (KOH). By using seaboard dextrose
agar at 25ºC and 37ºC the fungal culture was done. Periodically it was identified through culture
characteristics & microscopy if growth was present. Results: In this study, 118 culture positive
samples were included. In 82 cases Aspergillus Spp. was observed among positive specimens;
In 32 samples Aspergillus flavus was observed while in 10 samples Aspergillus fumigates was
found and species was not cleared in 40 samples. The fungal element was isolated in 36
samples but genus was not determined. Conclusion: In fungal nasal polyposis, Aspergillus
Spp. is very general pathogen and we observed in our study that Aspergillus flavus is very
common agent.