C-REACTIVE PROTEIN (CRP)

IN PATIENTS WITH METABOLIC SYNDROME

Abstract

Objective: To determine the frequency of raised C-reactive protein (CRP) in
patients with metabolic syndrome. Patients and methods: This cross sectional descriptive
study of six months study was conducted at Liaquat University Hospital Hyderabad. All the
patients of 20 to 60 years of age, of either gender presented with symptoms of metabolic
syndrome for more than 01 year duration were admitted and evaluated for C-reactive protein.
The data was analyzed in SPSS 16 and the frequency and percentage was calculated. Results:
Total one hundred patients (59 females and 41 males) with metabolic syndrome were evaluated
for C-reactive protein. The mean waist circumference for males and female patients with raised
CRP was 48.93±2.33 and 48.42±3.41 while the mean ±SD of serum triglycerides level for male
and female with raised CRP was 192.41±3.21 and 196.31±3.43 respectively. The mean ±SD of
serum HDL-C level for male and female with raised CRP was 28.32±1.22 and 25.31±1.42. The
mean ±SD of systolic and diastolic pressure for males and female patients with raised CRP was
150±3.42 and 100.51±4.42. The mean ±SD of serum fasting blood sugar for male and female
patients with raised CRP was 131.52±3.33 and 143.42±7.42 respectively. The mean ±SD of
CRP for male and female patients with raised CRP was 4.42±1.21 and 5.8±2.52. In relation
to gender distribution, the majority of subjects from 40-49 years of age group with female
predominance (p = 0.01) while the CRP was raised in 67% patients in relation to age (p=0.05)
and gender (p=0.04) respectively. Out of 67 subjects with raised CRP 44 were females and 23
were males.
Conclusions: The CRP was raised in patients with metabolic syndrome.