REFRACTORY MYASTHENIA GRAVIS

PATIENT ON RITUXIMAB WITH ACUTE RESPIRATORY FAILURE: A CASE REPORT

Authors

  • Muhammad Anees Post Graduate Medical Institute, Peshawar, Pakistan.
  • Jawaria Idrees Khyber Medical University, Peshawar, Pakistan.
  • Mashaal Arifullah Peshawar, Pakistan.
  • Saad Salman Lady Reading Hospital, PGMI, Peshawar.
  • Sudhair Abbas Peshawar, Pakistan.

DOI:

https://doi.org/10.29309/TPMJ/2015.22.03.1360

Keywords:

Rituximab, Myasthenia gravis, Respiratory failure

Abstract

Myasthenia gravis (MG) is prototypical neurological autoimmune disorder,
characterized by limb and occulo-bulbular fragility. Our case study will facilitate the practitioners
as well as the scientific community to consider other therapy plans with patients presented with
acute respiratory failure due to the use of rituximab.A 25-year-old man presented with acute
respiratory failure This case reporte sheds light on the importance of differential diagnoses of
refractory myasthenia gravis for inexplicable acute respiratory failure upon rituximab treatment.
The case study demonstrates the problems associated with use of rituximab in refractory
myasthenia gravis. It can cause acute respiratory failure among the patients with relapse
specially. Our case study will facilitate the practitioners as well as the scientific community to
consider other therapy plans with patients presented with acute respiratory failure due to the
use of rituximab.

Author Biographies

Muhammad Anees, Post Graduate Medical Institute, Peshawar, Pakistan.

Lady Reading Hospital

Mashaal Arifullah, Peshawar, Pakistan.

Department of Pharmacy

Sudhair Abbas, Peshawar, Pakistan.

Department of Pharmacy

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Published

2015-03-10